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England recorded 21,129 antibiotic-resistant bloodstream infections in 2025
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England recorded 21,129 cases of antibiotic-resistant bloodstream infection in 2025, up 3.2% from 20,468 in 2024, according to UK Health Security Agency surveillance figures released on 12 November. The total averages about 406 reported cases a week.
The rise was slower than the 9.3% increase recorded from 2023 to 2024. Compared with 2019, when 18,086 cases were reported, the latest annual count was 16.8% higher.
The agency also reported that antibiotic use in England’s NHS fell 10.7% between 2019 and 2025. This measures antibiotic consumption, which the agency tracks separately from reported infections.
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